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Vlahova A., Kyuchukov N., Yordanov V.,Tzvetanov S., Plamenova A., Stoyanova V., Baitchev G. Atypical hyperplasia of the breast-3 year experience. XI IMSC Pleven 2013, Bulgaria

Vlahova A., Kyuchukov N., Yordanov V.,Tzvetanov S., Plamenova A., Stoyanova V., Baitchev G. Atypical hyperplasia of the breast-3 year experience.

XI IMSC Pleven 2013, Bulgaria

 

INTRODUCTION: Atypical hyperplasia of the breast is of particular interest from an oncological perspective as it is associated with an increased risk (4-5 times) of progression to breast cancer.

AIM: The goal of this project is to analyze the clinicomorphological characteristics of patients with histologically verified atypical hyperplasia of the breast.

MATERIALS: This is a retrospective study of 34 patients with a morphologically proven atypical hyperplasia or lobular hyperplasia. All patients were diagnosed and operated in the Breast Unit of the Military Medical Academy in Sofia, Bulgaria for a 3-year period (2010-2012).

METHODS: All patients underwent preoperative triple diagnosis, which included: clinical examination, ultrasonography and cytological examination of fine needle aspiration biopsy.

RESULTS: Our findings showed that 23 of the cases are due to atypical ductal hyperplasia, whereas the remaining 11 are due to atypical lobular hyperplasia. In the majority of cases we discovered other accompanying benign breast diseases. Of all patients, 6 women had a family history for breast cancer. In just one third of all patients there was preoperative evidence revealing atypical hyperplasia.

CONCLUSION: The high risk of breast cancer progression is a sufficient reason for us to recommend mandatory biopsy, active follow-up and observation in dynamics of all suspicious breast lesions.

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